The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a small-spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Campylobacter, Clostridium, Corynebacterium, Erysipelothrix, Haemophilus, Listeria, Pasteurella, penicillinase negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Klebsiella, Pasteurella, Salmonella and Staphylococcus spp.

INDICATIONS:

Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp., in calves, cattle, goats, sheep and swine.

DOSAGE AND ADMINISTRATION:

For intramuscular administration. Never intravenously. Shake well before use.

Cattle , horses: 1 ml. per 20 kg. body weight daily for 3-5 days.

Sheep, goats, and pigs : 1 ml. per 20 kg. body weight daily for 3-5 days.

Young animals: Dosage 50% higher.

CONTRAINDICATIONS:

- Hypersensitivity to penicillin, procaine and/or aminoglycosides.

- Administration to animals with a serious impaired renal function.

- Concurrent administration with tetracyclines, chloramphenicol, macrolides and lincosamides.

SIDE EFFECTS:

- Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows.

- Ototoxity, neurotoxicity or nephrotoxicity.

- Hypersensitivity reactions.

WITHDRAWAL TIMES:

- For kidney : 45 days.

- For meat : 21 days.

- For milk : 3 days.

WARING:

Keep out of reach of children.